Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties

The origin and evolution of the complex regulatory landscapes of some vertebrate developmental genes, often spanning hundreds of Kbp and including neighboring genes, remain poorly understood. The Sonic Hedgehog (Shh) genomic regulatory block (GRB) is one of the best functionally characterized exampl...

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Detalles Bibliográficos
Autores principales: Irimia, Manuel, Royo, Jose L., Burguera, Demian, Maeso, Ignacio, Gómez-Skarmeta, José L., Garcia-Fernandez, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364491/
https://www.ncbi.nlm.nih.gov/pubmed/22666536
http://dx.doi.org/10.1038/srep00433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364491/
https://www.ncbi.nlm.nih.gov/pubmed/22666536
http://dx.doi.org/10.1038/srep00433

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