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Whole-Genome Profiling of a Novel Mutagenesis Technique Using Proofreading-Deficient DNA Polymerase δ

A novel mutagenesis technique using error-prone DNA polymerase δ (polδ), the disparity mutagenesis model of evolution, has been successfully employed to generate novel microorganism strains with desired traits. However, little else is known about the spectra of mutagenic effects caused by disparity...

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Detalles Bibliográficos
Autores principales:	Shiwa, Yuh, Fukushima-Tanaka, Sanae, Kasahara, Ken, Horiuchi, Takayuki, Yoshikawa, Hirofumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364565/ https://www.ncbi.nlm.nih.gov/pubmed/22675654 http://dx.doi.org/10.1155/2012/860797

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