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The immunoregulatory effects of CMV-infection in human fibroblasts and the impact on cellular senescence
BACKGROUND: As a chronic antigenic stressor human Cytomegalovirus (CMV) contributes substantially to age-related alterations of the immune system. Even though monocytes have the greatest propensity for CMV-infection and seem to be an important host for the virus during latency, fibroblasts are also...
Autores principales: | Wolf, Juliane, Weinberger, Birgit, Grubeck-Loebenstein, Beatrix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364840/ https://www.ncbi.nlm.nih.gov/pubmed/22455503 http://dx.doi.org/10.1186/1742-4933-9-1 |
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