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Improved negative selection protocol for Plasmodium berghei in the rodent malarial model
An improved methodology is presented here for transgenic Plasmodium berghei lines that express the negative selectable marker yFCU (a bifunctional protein that combines yeast cytosine deaminase and uridyl phosphoribosyl transferase (UPRT)) and substitutes delivery of selection drug 5-fluorocytosine...
Autores principales: | Orr, Rachael Y, Philip, Nisha, Waters, Andrew P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364864/ https://www.ncbi.nlm.nih.gov/pubmed/22463060 http://dx.doi.org/10.1186/1475-2875-11-103 |
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