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Improved negative selection protocol for Plasmodium berghei in the rodent malarial model

An improved methodology is presented here for transgenic Plasmodium berghei lines that express the negative selectable marker yFCU (a bifunctional protein that combines yeast cytosine deaminase and uridyl phosphoribosyl transferase (UPRT)) and substitutes delivery of selection drug 5-fluorocytosine...

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Detalles Bibliográficos
Autores principales: Orr, Rachael Y, Philip, Nisha, Waters, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364864/
https://www.ncbi.nlm.nih.gov/pubmed/22463060
http://dx.doi.org/10.1186/1475-2875-11-103

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