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The CanOE Strategy: Integrating Genomic and Metabolic Contexts across Multiple Prokaryote Genomes to Find Candidate Genes for Orphan Enzymes

Of all biochemically characterized metabolic reactions formalized by the IUBMB, over one out of four have yet to be associated with a nucleic or protein sequence, i.e. are sequence-orphan enzymatic activities. Few bioinformatics annotation tools are able to propose candidate genes for such activitie...

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Detalles Bibliográficos
Autores principales: Smith, Adam Alexander Thil, Belda, Eugeni, Viari, Alain, Medigue, Claudine, Vallenet, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364942/
https://www.ncbi.nlm.nih.gov/pubmed/22693442
http://dx.doi.org/10.1371/journal.pcbi.1002540

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