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The CanOE Strategy: Integrating Genomic and Metabolic Contexts across Multiple Prokaryote Genomes to Find Candidate Genes for Orphan Enzymes
Of all biochemically characterized metabolic reactions formalized by the IUBMB, over one out of four have yet to be associated with a nucleic or protein sequence, i.e. are sequence-orphan enzymatic activities. Few bioinformatics annotation tools are able to propose candidate genes for such activitie...
Autores principales: | Smith, Adam Alexander Thil, Belda, Eugeni, Viari, Alain, Medigue, Claudine, Vallenet, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364942/ https://www.ncbi.nlm.nih.gov/pubmed/22693442 http://dx.doi.org/10.1371/journal.pcbi.1002540 |
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