Transmitted/Founder and Chronic Subtype C HIV-1 Use CD4 and CCR5 Receptors with Equal Efficiency and Are Not Inhibited by Blocking the Integrin α4β7

Sexual transmission of human immunodeficiency virus type 1 (HIV-1) most often results from productive infection by a single transmitted/founder (T/F) virus, indicating a stringent mucosal bottleneck. Understanding the viral traits that overcome this bottleneck could have important implications for H...

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Detalles Bibliográficos
Autores principales: Parrish, Nicholas F., Wilen, Craig B., Banks, Lauren B., Iyer, Shilpa S., Pfaff, Jennifer M., Salazar-Gonzalez, Jesus F., Salazar, Maria G., Decker, Julie M., Parrish, Erica H., Berg, Anna, Hopper, Jennifer, Hora, Bhavna, Kumar, Amit, Mahlokozera, Tatenda, Yuan, Sally, Coleman, Charl, Vermeulen, Marion, Ding, Haitao, Ochsenbauer, Christina, Tilton, John C., Permar, Sallie R., Kappes, John C., Betts, Michael R., Busch, Michael P., Gao, Feng, Montefiori, David, Haynes, Barton F., Shaw, George M., Hahn, Beatrice H., Doms, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364951/
https://www.ncbi.nlm.nih.gov/pubmed/22693444
http://dx.doi.org/10.1371/journal.ppat.1002686

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