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Experimental Evolution of Legionella pneumophila in Mouse Macrophages Leads to Strains with Altered Determinants of Environmental Survival

The Gram-negative bacterium, Legionella pneumophila, is a protozoan parasite and accidental intracellular pathogen of humans. We propose a model in which cycling through multiple protozoan hosts in the environment holds L. pneumophila in a state of evolutionary stasis as a broad host-range pathogen....

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Detalles Bibliográficos
Autores principales:	Ensminger, Alexander W., Yassin, Yosuf, Miron, Alexander, Isberg, Ralph R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364954/ https://www.ncbi.nlm.nih.gov/pubmed/22693450 http://dx.doi.org/10.1371/journal.ppat.1002731

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