Tumor Necrosis Factor α Inhibits Expression of the Iron Regulating Hormone Hepcidin in Murine Models of Innate Colitis

BACKGROUND: Abnormal expression of the liver peptide hormone hepcidin, a key regulator of iron homeostasis, contributes to the pathogenesis of anemia in conditions such as inflammatory bowel disease (IBD). Since little is known about the mechanisms that control hepcidin expression during states of i...

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Detalles Bibliográficos
Autores principales: Shanmugam, Nanda Kumar N., Ellenbogen, Shiri, Trebicka, Estela, Wang, Lijian, Mukhopadhyay, Subhankar, Lacy-Hulbert, Adam, Gallini, Carey Ann, Garrett, Wendy S., Cherayil, Bobby J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365004/
https://www.ncbi.nlm.nih.gov/pubmed/22675442
http://dx.doi.org/10.1371/journal.pone.0038136

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