Extensive Gene-Specific Translational Reprogramming in a Model of B Cell Differentiation and Abl-Dependent Transformation

To what extent might the regulation of translation contribute to differentiation programs, or to the molecular pathogenesis of cancer? Pre-B cells transformed with the viral oncogene v-Abl are suspended in an immortalized, cycling state that mimics leukemias with a BCR-ABL1 translocation, such as Ch...

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Detalles Bibliográficos
Autores principales: Bates, Jamie G., Salzman, Julia, May, Damon, Garcia, Patty B., Hogan, Gregory J., McIntosh, Martin, Schlissel, Mark S., Brown, Pat O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365017/
https://www.ncbi.nlm.nih.gov/pubmed/22693568
http://dx.doi.org/10.1371/journal.pone.0037108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365017/
https://www.ncbi.nlm.nih.gov/pubmed/22693568
http://dx.doi.org/10.1371/journal.pone.0037108

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