HIV Delays IFN-α Production from Human Plasmacytoid Dendritic Cells and Is Associated with SYK Phosphorylation

Plasmacytoid dendritic cells (pDC) are the major producers of type I interferons (IFNs) in humans and rapidly produce IFN-α in response to virus exposure. Although HIV infection is associated with pDC activation, it is unclear why the innate immune response is unable to effectively control viral rep...

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Detalles Bibliográficos
Autores principales: Lo, Calvin C., Schwartz, Jordan A., Johnson, Dylan J., Yu, Monica, Aidarus, Nasra, Mujib, Shariq, Benko, Erika, Hyrcza, Martin, Kovacs, Colin, Ostrowski, Mario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365039/
https://www.ncbi.nlm.nih.gov/pubmed/22693567
http://dx.doi.org/10.1371/journal.pone.0037052

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