Cargando…

Dysregulation of Macrophage-Secreted Cathepsin B Contributes to HIV-1-Linked Neuronal Apoptosis

Chronic HIV infection leads to the development of cognitive impairments, designated as HIV-associated neurocognitive disorders (HAND). The secretion of soluble neurotoxic factors by HIV-infected macrophages plays a central role in the neuronal dysfunction and cell death associated with HAND. One pot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodriguez-Franco, Eillen J., Cantres-Rosario, Yisel M., Plaud-Valentin, Marines, Romeu, Rafael, Rodríguez, Yolanda, Skolasky, Richard, Meléndez, Viviana, Cadilla, Carmen L., Melendez, Loyda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365072/ https://www.ncbi.nlm.nih.gov/pubmed/22693552 http://dx.doi.org/10.1371/journal.pone.0036571

Ejemplares similares

Late HIV infection modulates the expression and activity of Cathepsin B, and its inhibitors in macrophages: implications in neuropathogenesis
por: Rodriguez, Eillen, et al.
Publicado: (2010)

HIV Infection Induces Extracellular Cathepsin B Uptake and Damage to Neurons
por: Cantres-Rosario, Yisel M., et al.
Publicado: (2019)

Microwave & magnetic proteomics of macrophages from patients with HIV-associated cognitive impairment
por: Cantres-Rosario, Yisel M., et al.
Publicado: (2017)

Macrophage Derived Cystatin B/Cathepsin B in HIV Replication and Neuropathogenesis
por: Rivera, Linda E., et al.
Publicado: (2014)

Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways
por: Zenón-Meléndez, Camille N., et al.
Publicado: (2022)

Proteomic Analysis of HIV-Infected Macrophages
por: Meléndez, Loyda M., et al.
Publicado: (2010)

Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine
por: López, Omar Vélez, et al.
Publicado: (2018)

Cannabinoid receptor type 2 agonist JWH-133 decreases cathepsin B secretion and neurotoxicity from HIV-infected macrophages
por: Rosario-Rodríguez, Lester J., et al.
Publicado: (2022)

Soluble Insulin Receptor Levels in Plasma, Exosomes, and Urine and Its Association With HIV-Associated Neurocognitive Disorders
por: Cantres-Rosario, Yisel M., et al.
Publicado: (2022)

Differential protein expression profile in the hypothalamic GT1-7 cell line after exposure to anabolic androgenic steroids
por: Martínez-Rivera, Freddyson J., et al.
Publicado: (2017)

Decreased CSTB, RAGE, and Axl Receptor Are Associated with Zika Infection in the Human Placenta
por: Borges-Vélez, Gabriel, et al.
Publicado: (2022)

Zika virus infection of the placenta alters extracellular matrix proteome
por: Borges-Vélez, Gabriel, et al.
Publicado: (2021)

The Characterization and Evaluation of the Soluble Triggering Receptor Expressed on Myeloid Cells-like Transcript-1 in Stable Coronary Artery Disease
por: Bayrón-Marrero, Zaida, et al.
Publicado: (2023)

Differential Regulation of Cathepsin S and Cathepsin L in Interferon γ–treated Macrophages
por: Beers, Courtney, et al.
Publicado: (2003)

Maternal plasma viral load and neutralizing/enhancing antibodies in vertical transmission of HIV: A non-randomized prospective study
por: Kamara, Paul, et al.
Publicado: (2005)

The involvement of Cathepsin B and L in inflammation and cholesterol trafficking protein NPC2 secretion in macrophages
por: Hannaford, Jennifer, et al.
Publicado: (2013)

A fluorogenic, peptide-based probe for the detection of Cathepsin D in macrophages
por: Rodriguez-Rios, Maria, et al.
Publicado: (2023)

Cathepsin D in breast secretions from women with breast cancer.
por: Sánchez, L. M., et al.
Publicado: (1993)

Cathepsin L secretion by host and neoplastic cells potentiates invasion
por: Dykes, Samantha S., et al.
Publicado: (2019)

Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages
por: Tsukuba, Takayuki, et al.
Publicado: (2013)

Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages
por: Pires, David, et al.
Publicado: (2016)

Cathepsins in Bacteria-Macrophage Interaction: Defenders or Victims of Circumstance?
por: Szulc-Dąbrowska, Lidia, et al.
Publicado: (2020)

Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction
por: Chevriaux, Angélique, et al.
Publicado: (2020)

The role of the muscarinic system in regulating estradiol secretion varies during the estrous cycle: the hemiovariectomized rat model
por: Cruz, María E, et al.
Publicado: (2006)

Correction: Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages
Publicado: (2014)

Cathepsin Inhibition Modulates Metabolism and Polarization of Tumor-Associated Macrophages
por: Oelschlaegel, Diana, et al.
Publicado: (2020)

TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins
por: Kundu, Samrat T., et al.
Publicado: (2018)

Practical context of enzymatic treatment for wound healing: A secreted protease approach (Review)
por: Isabela Avila-Rodríguez, María, et al.
Publicado: (2020)

Mechanisms of the Regulation and Dysregulation of Glucagon Secretion
por: Onyango, Arnold N.
Publicado: (2020)

Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells
por: Fu, Runzhong, et al.
Publicado: (2021)

Impact of Enniatin B and Beauvericin on Lysosomal Cathepsin B Secretion and Apoptosis Induction
por: Aufy, Mohammed, et al.
Publicado: (2023)

Effects of Vacuolar H(+)-ATPase Inhibition on Activation of Cathepsin B and Cathepsin L Secreted from MDA-MB231 Breast Cancer Cells
por: Uhlman, Andrew, et al.
Publicado: (2017)

The acute asymmetric effects of hemiovariectomy on testosterone secretion vary along the estrous cycle. The participation of the cholinergic system
por: Flores, Angélica, et al.
Publicado: (2006)

Sexually transmitted diseases during the COVID-19 pandemic: A focus on syphilis and gonorrhoea in Cuba
por: Rodríguez, Islay, et al.
Publicado: (2020)

Redundant or separate entities?—roles of Twist1 and Twist2 as molecular switches during gene transcription
por: Franco, Hector L., et al.
Publicado: (2011)

Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors
por: Casasnovas-Nieves, José J., et al.
Publicado: (2023)

THE ESTIMATION OF CATHEPSIN WITH HEMOGLOBIN AND THE PARTIAL PURIFICATION OF CATHEPSIN
por: Anson, M. L.
Publicado: (1937)

Systemic Angiopoietin-1/2 Dysregulation in Pediatric Sepsis and Septic Shock
por: Melendez, Elliot, et al.
Publicado: (2019)

The Zoonotic Helminth Parasite Fasciola hepatica: Virulence-Associated Cathepsin B and Cathepsin L Cysteine Peptidases Secreted by Infective Newly Excysted Juveniles (NEJ)
por: Barbour, Tara, et al.
Publicado: (2021)

Melanocortin Receptors as Novel Effectors of Macrophage Responses in Inflammation
por: Patel, Hetal B., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0ltl7p7skscttitabnn9610cr4