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High Salt Intake Down-Regulates Colonic Mineralocorticoid Receptors, Epithelial Sodium Channels and 11β-Hydroxysteroid Dehydrogenase Type 2

Besides the kidneys, the gastrointestinal tract is the principal organ responsible for sodium homeostasis. For sodium transport across the cell membranes the epithelial sodium channel (ENaC) is of pivotal relevance. The ENaC is mainly regulated by mineralocorticoid receptor mediated actions. The MR...

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Detalles Bibliográficos
Autores principales:	Lienhard, Daniel, Lauterburg, Meret, Escher, Geneviève, Frey, Felix J., Frey, Brigitte M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365073/ https://www.ncbi.nlm.nih.gov/pubmed/22693583 http://dx.doi.org/10.1371/journal.pone.0037898

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