Cargando…

Translational Control through eIF2alpha Phosphorylation during the Leishmania Differentiation Process

The parasitic protozoan Leishmania alternates between an invertebrate and a mammalian host. Upon their entry to mammalian macrophages, Leishmania promastigotes differentiate into amastigote forms within the harsh environment of the phagolysosomal compartment. Here, we provide evidence for the import...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cloutier, Serge, Laverdière, Maxime, Chou, Marie-Noelle, Boilard, Nathalie, Chow, Conan, Papadopoulou, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365078/ https://www.ncbi.nlm.nih.gov/pubmed/22693545 http://dx.doi.org/10.1371/journal.pone.0035085

Ejemplares similares

eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
por: Jennings, Martin D., et al.
Publicado: (2010)

The structural basis of translational control by eIF2 phosphorylation
por: Adomavicius, Tomas, et al.
Publicado: (2019)

The translational factor eIF3f: the ambivalent eIF3 subunit
por: Marchione, Roberta, et al.
Publicado: (2013)

Analysis of the Antigenic and Prophylactic Properties of the Leishmania Translation Initiation Factors eIF2 and eIF2B in Natural and Experimental Leishmaniasis
por: Garde, Esther, et al.
Publicado: (2018)

Light-regulated translational control of circadian behavior by eIF4E phosphorylation
por: Cao, Ruifeng, et al.
Publicado: (2015)

Stress-induced inhibition of translation independently of eIF2α phosphorylation
por: Knutsen, Jon Halvor Jonsrud, et al.
Publicado: (2015)

Structural basis for the inhibition of translation through eIF2α phosphorylation
por: Gordiyenko, Yuliya, et al.
Publicado: (2019)

Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions
por: Yoffe, Yael, et al.
Publicado: (2009)

Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions
por: Chen, Yi-Jiun, et al.
Publicado: (2010)

A Retrospective on eIF2A—and Not the Alpha Subunit of eIF2
por: Komar, Anton A., et al.
Publicado: (2020)

eIF4E Phosphorylation in Prostate Cancer()()
por: D'Abronzo, Leandro S., et al.
Publicado: (2018)

Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation
por: Schneider, Kim, et al.
Publicado: (2020)

Circadian clock control of eIF2α phosphorylation is necessary for rhythmic translation initiation
por: Karki, Shanta, et al.
Publicado: (2020)

Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation
por: Bogorad, Andrew M., et al.
Publicado: (2017)

eIF4B phosphorylation at Ser504 links synaptic activity with protein translation in physiology and pathology
por: Bettegazzi, Barbara, et al.
Publicado: (2017)

Translation of Sindbis Subgenomic mRNA is Independent of eIF2, eIF2A and eIF2D
por: Sanz, Miguel Angel, et al.
Publicado: (2017)

Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3
por: Robichaud, Nathaniel, et al.
Publicado: (2014)

Mutational analysis of the alpha subunit of eIF2B provides insights into the role of eIF2B bodies in translational control and VWM disease
por: Norris, Karl, et al.
Publicado: (2021)

Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex
por: Erzberger, Jan P., et al.
Publicado: (2014)

Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex
por: Erzberger, Jan P., et al.
Publicado: (2014)

Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine
por: Huang, Wei, et al.
Publicado: (2016)

Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα
por: Baird, Thomas D., et al.
Publicado: (2014)

Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes
por: Jennings, Martin D, et al.
Publicado: (2017)

4E-BP restrains eIF4E phosphorylation
por: Müller, David, et al.
Publicado: (2013)

eIF4B, eIF4G and RNA regulate eIF4A activity in translation initiation by modulating the eIF4A conformational cycle
por: Harms, Ulf, et al.
Publicado: (2014)

eIF4E Phosphorylation Influences Bdnf mRNA Translation in Mouse Dorsal Root Ganglion Neurons
por: Moy, Jamie K., et al.
Publicado: (2018)

Loss of eIF4E Phosphorylation Engenders Depression-like Behaviors via Selective mRNA Translation
por: Amorim, Inês S., et al.
Publicado: (2018)

ER Stress-Induced eIF2-alpha Phosphorylation Underlies Sensitivity of Striatal Neurons to Pathogenic Huntingtin
por: Leitman, Julia, et al.
Publicado: (2014)

The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells
por: González-Almela, Esther, et al.
Publicado: (2018)

Enzymatic and Molecular Characterization of Anti-Leishmania Molecules That Differently Target Leishmania and Mammalian eIF4A Proteins, LieIF4A and eIF4A(Mus)
por: Abdelkrim, Yosser Zina, et al.
Publicado: (2022)

Characterization of an Atypical eIF4E Ortholog in Leishmania, LeishIF4E-6
por: Tupperwar, Nitin, et al.
Publicado: (2021)

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly
por: Sidrauski, Carmela, et al.
Publicado: (2015)

Ribosome profiling uncovers selective mRNA translation associated with eIF2 phosphorylation in erythroid progenitors
por: Paolini, Nahuel A., et al.
Publicado: (2018)

eIF2B promotes eIF5 dissociation from eIF2•GDP to facilitate guanine nucleotide exchange for translation initiation
por: Jennings, Martin D., et al.
Publicado: (2013)

Embraced by eIF3: structural and functional insights into the roles of eIF3 across the translation cycle
por: Valášek, Leoš Shivaya, et al.
Publicado: (2017)

Phosphorylation independent eIF4E translational reprogramming of selective mRNAs determines tamoxifen resistance in breast cancer
por: Gong, Chun, et al.
Publicado: (2020)

Translation, Pdcd4 and eIF4A
por: Biyanee, Abhiruchi, et al.
Publicado: (2015)

Loss-of-Function Analysis Reveals Distinct Requirements of the Translation Initiation Factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila Spermatogenesis
por: Ghosh, Sanjay, et al.
Publicado: (2015)

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice
por: Halliday, Mark, et al.
Publicado: (2017)

Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E)
por: Sun, Rui, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_gn04fqnvkrs1f51bpsaf5tjl4c