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Robust Quantification of Polymerase Chain Reactions Using Global Fitting

BACKGROUND: Quantitative polymerase chain reactions (qPCR) are used to monitor relative changes in very small amounts of DNA. One drawback to qPCR is reproducibility: measuring the same sample multiple times can yield data that is so noisy that important differences can be dismissed. Numerous analyt...

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Detalles Bibliográficos
Autores principales: Carr, Ana C., Moore, Sean D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365123/
https://www.ncbi.nlm.nih.gov/pubmed/22701526
http://dx.doi.org/10.1371/journal.pone.0037640