Deletion of HIF-1α partially rescues the abnormal hyaloid vascular system in Cited2 conditional knockout mouse eyes

PURPOSE: Cited2 (CBP/p300-interacting transactivators with glutamic acid (E) and aspartic acid (D)-rich tail 2) is a member of a new family of transcriptional modulators. Cited2 null embryos exhibit hyaloid hypercellularity consisting of aberrant vasculature in the eye. The purpose of the study is t...

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Detalles Bibliográficos
Autores principales: Huang, Tai-Qin, Wang, Yiwei, Ebrahem, Quteba, Chen, Yu, Cheng, Cindy, Doughman, Yong Qiu, Watanabe, Michiko, Dunwoodie, Sally L., Yang, Yu-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365139/
https://www.ncbi.nlm.nih.gov/pubmed/22665973

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