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TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders

TCF4 is involved in neurodevelopment, and intergenic and intronic variants in or close to the TCF4 gene have been associated with susceptibility to schizophrenia. However, the functional role of TCF4 at the level of gene expression and relationship to severity of core psychotic phenotypes are not kn...

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Detalles Bibliográficos
Autores principales: Wirgenes, K V, Sønderby, I E, Haukvik, U K, Mattingsdal, M, Tesli, M, Athanasiu, L, Sundet, K, Røssberg, J I, Dale, A M, Brown, A A, Agartz, I, Melle, I, Djurovic, S, Andreassen, O A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365258/
https://www.ncbi.nlm.nih.gov/pubmed/22832956
http://dx.doi.org/10.1038/tp.2012.39