Abrogated cryptic activation of lentiviral transfer vectors

Despite significant improvements in lentivirus (LV) vector-based gene therapy there are still several safety risks using LV vectors including the potential formation of replication-competent LV particles. To address this shortcoming, we constructed a novel and safer gene transfer system using modifi...

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Detalles Bibliográficos
Autores principales: Luche, Ralf M., Enssle, Joerg, Kiem, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365281/
https://www.ncbi.nlm.nih.gov/pubmed/22666541
http://dx.doi.org/10.1038/srep00438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365281/
https://www.ncbi.nlm.nih.gov/pubmed/22666541
http://dx.doi.org/10.1038/srep00438

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