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Explicit hypoxia targeting with tumor suppression by creating an “obligate” anaerobic Salmonella Typhimurium strain

Using bacteria as therapeutic agents against solid tumors is emerging as an area of great potential in the treatment of cancer. Obligate and facultative anaerobic bacteria have been shown to infiltrate the hypoxic regions of solid tumors, thereby reducing their growth rate or causing regression. How...

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Detalles Bibliográficos
Autores principales: Yu, Bin, Yang, Mei, Shi, Lei, Yao, Yandan, Jiang, Qinqin, Li, Xuefei, Tang, Lei-Han, Zheng, Bo-Jian, Yuen, Kwok-Yung, Smith, David K., Song, Erwei, Huang, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365283/
https://www.ncbi.nlm.nih.gov/pubmed/22666539
http://dx.doi.org/10.1038/srep00436