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Challenge and promise: the role of miRNA for pathogenesis and progression of malignant melanoma
microRNAs are endogenous noncoding RNAs that are implicated in gene regulation. More recently, miRNAs have been shown to play a pivotal role in multiple cellular processes that interfere with tumorigenesis. Here we summarize the essential role of microRNAs for human cancer with special focus on mali...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365361/ https://www.ncbi.nlm.nih.gov/pubmed/22704085 http://dx.doi.org/10.1007/s13148-010-0001-7 |
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author | Essa, Salma Denzer, N. Mahlknecht, U. Klein, R. Collnot, E. M. Reichrath, J. |
author_facet | Essa, Salma Denzer, N. Mahlknecht, U. Klein, R. Collnot, E. M. Reichrath, J. |
author_sort | Essa, Salma |
collection | PubMed |
description | microRNAs are endogenous noncoding RNAs that are implicated in gene regulation. More recently, miRNAs have been shown to play a pivotal role in multiple cellular processes that interfere with tumorigenesis. Here we summarize the essential role of microRNAs for human cancer with special focus on malignant melanoma and the promising perspectives for cancer therapies. |
format | Online Article Text |
id | pubmed-3365361 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-33653612012-06-02 Challenge and promise: the role of miRNA for pathogenesis and progression of malignant melanoma Essa, Salma Denzer, N. Mahlknecht, U. Klein, R. Collnot, E. M. Reichrath, J. Clin Epigenetics Review microRNAs are endogenous noncoding RNAs that are implicated in gene regulation. More recently, miRNAs have been shown to play a pivotal role in multiple cellular processes that interfere with tumorigenesis. Here we summarize the essential role of microRNAs for human cancer with special focus on malignant melanoma and the promising perspectives for cancer therapies. Springer-Verlag 2010-05-08 /pmc/articles/PMC3365361/ /pubmed/22704085 http://dx.doi.org/10.1007/s13148-010-0001-7 Text en © Springer-Verlag 2010 |
spellingShingle | Review Essa, Salma Denzer, N. Mahlknecht, U. Klein, R. Collnot, E. M. Reichrath, J. Challenge and promise: the role of miRNA for pathogenesis and progression of malignant melanoma |
title | Challenge and promise: the role of miRNA for pathogenesis and progression of malignant melanoma |
title_full | Challenge and promise: the role of miRNA for pathogenesis and progression of malignant melanoma |
title_fullStr | Challenge and promise: the role of miRNA for pathogenesis and progression of malignant melanoma |
title_full_unstemmed | Challenge and promise: the role of miRNA for pathogenesis and progression of malignant melanoma |
title_short | Challenge and promise: the role of miRNA for pathogenesis and progression of malignant melanoma |
title_sort | challenge and promise: the role of mirna for pathogenesis and progression of malignant melanoma |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365361/ https://www.ncbi.nlm.nih.gov/pubmed/22704085 http://dx.doi.org/10.1007/s13148-010-0001-7 |
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