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Histone deacetylase inhibitors: clinical implications for hematological malignancies
Histone modifications have widely been implicated in cancer development and progression and are potentially reversible by drug treatments. The N-terminal tails of each histone extend outward through the DNA strand containing amino acid residues modified by posttranslational acetylation, methylation,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365365/ https://www.ncbi.nlm.nih.gov/pubmed/22704087 http://dx.doi.org/10.1007/s13148-010-0006-2 |