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Insufficient DNA methylation affects healthy aging and promotes age-related health problems
DNA methylation plays an integral role in development and aging through epigenetic regulation of genome function. DNA methyltransferase 1 (Dnmt1) is the most prevalent DNA methyltransferase that maintains genomic methylation stability. To further elucidate the function of Dnmt1 in aging and age-rela...
Autores principales: | Liu, Liang, van Groen, Thomas, Kadish, Inga, Li, Yuanyuan, Wang, Deli, James, Smitha R., Karpf, Adam R., Tollefsbol, Trygve O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365396/ https://www.ncbi.nlm.nih.gov/pubmed/22704347 http://dx.doi.org/10.1007/s13148-011-0042-6 |
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