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Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia

Epigenetic mechanisms such as DNA hypermethylation and modifications of histone amino acids are known to play an important role in the control of gene expression both in normal human development and tumorigenesis. Hypermethylation of CpG islands within promoter regions of tumor suppressor genes is a...

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Detalles Bibliográficos
Autores principales:	Oing, Christoph, Jost, Edgar, Dahl, Edgar, Wilop, Stefan, Brümmendorf, Tim H., Galm, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365397/ https://www.ncbi.nlm.nih.gov/pubmed/22704354 http://dx.doi.org/10.1007/s13148-011-0043-5

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