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H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues
A sequence variant of histone H2A called H2AX is one of the key components of chromatin involved in DNA damage response induced by different genotoxic stresses. Phosphorylated H2AX (γH2AX) is rapidly concentrated in chromatin domains around DNA double-strand breaks (DSBs) after the action of ionizin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer-Verlag
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365398/ https://www.ncbi.nlm.nih.gov/pubmed/22704343 http://dx.doi.org/10.1007/s13148-011-0044-4 |