Cargando…
H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues
A sequence variant of histone H2A called H2AX is one of the key components of chromatin involved in DNA damage response induced by different genotoxic stresses. Phosphorylated H2AX (γH2AX) is rapidly concentrated in chromatin domains around DNA double-strand breaks (DSBs) after the action of ionizin...
Autores principales: | Firsanov, Denis V., Solovjeva, Liudmila V., Svetlova, Maria P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365398/ https://www.ncbi.nlm.nih.gov/pubmed/22704343 http://dx.doi.org/10.1007/s13148-011-0044-4 |
Ejemplares similares
-
DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts
por: Solovjeva, Ljudmila, et al.
Publicado: (2015) -
The Impact of NAD Bioavailability on DNA Double-Strand Break Repair Capacity in Human Dermal Fibroblasts after Ionizing Radiation
por: Svetlova, Maria, et al.
Publicado: (2023) -
Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks
por: Rybak, Paulina, et al.
Publicado: (2016) -
DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner
por: Collins, Patrick L., et al.
Publicado: (2020) -
DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin
por: Jakob, Burkhard, et al.
Publicado: (2011)