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Co-transcriptional degradation of aberrant pre-mRNA by Xrn2

Eukaryotic protein-coding genes are transcribed as pre-mRNAs that are matured by capping, splicing and cleavage and polyadenylation. Although human pre-mRNAs can be long and complex, containing multiple introns and many alternative processing sites, they are usually processed co-transcriptionally. M...

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Detalles Bibliográficos
Autores principales: Davidson, Lee, Kerr, Alastair, West, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365414/
https://www.ncbi.nlm.nih.gov/pubmed/22522706
http://dx.doi.org/10.1038/emboj.2012.101

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