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Co-transcriptional degradation of aberrant pre-mRNA by Xrn2
Eukaryotic protein-coding genes are transcribed as pre-mRNAs that are matured by capping, splicing and cleavage and polyadenylation. Although human pre-mRNAs can be long and complex, containing multiple introns and many alternative processing sites, they are usually processed co-transcriptionally. M...
Autores principales: | Davidson, Lee, Kerr, Alastair, West, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365414/ https://www.ncbi.nlm.nih.gov/pubmed/22522706 http://dx.doi.org/10.1038/emboj.2012.101 |
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