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The C-terminal tail domain of metavinculin, vinculin’s splice variant, severs actin filaments

Vinculin and its splice variant, metavinculin (MV), are key elements of multiple protein assemblies linking the extracellular matrix to the actin cytoskeleton. Vinculin is expressed ubiquitously, whereas MV is mainly expressed in smooth and cardiac muscle tissue. The only difference in amino acid se...

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Detalles Bibliográficos
Autores principales: Janssen, Mandy E.W., Liu, HongJun, Volkmann, Niels, Hanein, Dorit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365496/
https://www.ncbi.nlm.nih.gov/pubmed/22613835
http://dx.doi.org/10.1083/jcb.201111046