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Osteopontin in Systemic Sclerosis and its Role in Dermal Fibrosis
Osteopontin (OPN) is a matricellular protein with proinflammatory and profibrotic properties. Previous reports demonstrate a role for OPN in wound healing and pulmonary fibrosis. Herein, we determined if OPN levels are increased in a large cohort of systemic sclerosis (SSc) patients and if OPN contr...
Autores principales: | Wu, Minghua, Schneider, Daniel J., Mayes, Maureen D, Assassi, Shervin, Arnett, Frank C., Tan, Filemon K., Blackburn, Michael R., Agarwal, Sandeep K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365548/ https://www.ncbi.nlm.nih.gov/pubmed/22402440 http://dx.doi.org/10.1038/jid.2012.32 |
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