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Functional analysis of the protein phosphatase activity of PTEN

In vitro, the tumour suppressor PTEN (phosphatase and tensin homologue deleted on chromosome 10) displays intrinsic phosphatase activity towards both protein and lipid substrates. In vivo, the lipid phosphatase activity of PTEN, through which it dephosphorylates the 3 position in the inositol sugar...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaoqun Catherine, Piccini, Antonella, Myers, Michael P., Van Aelst, Linda, Tonks, Nicholas K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365644/ https://www.ncbi.nlm.nih.gov/pubmed/22413754 http://dx.doi.org/10.1042/BJ20120098

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