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Upper and Lower Gastrointestinal Findings in PTEN Mutation–Positive Cowden Syndrome Patients Participating in an Active Surveillance Program

OBJECTIVES: Cowden syndrome (CS), associated with germline PTEN mutations, is an autosomal-dominant disorder with increased frequencies of thyroid and breast cancers. Recent reports document the occurrence of gastrointestinal (GI) polyps and increased risk of colon cancer in PTEN mutation carriers....

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Detalles Bibliográficos
Autores principales: Levi, Zohar, Baris, Hagit N, Kedar, Inbal, Niv, Yaron, Geller, Alex, Gal, Eyal, Gingold, Rachel, Morgenstern, Sara, Baruch, Yacov, Leach, Brandie Heald, Bronner, Mary P, Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365666/
https://www.ncbi.nlm.nih.gov/pubmed/23238744
http://dx.doi.org/10.1038/ctg.2011.4