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Dual TNF-α/Cyclin D1 Gene Silencing With an Oral Polymeric Microparticle System as a Novel Strategy for the Treatment of Inflammatory Bowel Disease

OBJECTIVES: RNA silencing utilizing short interfering RNA (siRNA) offers a new and exciting means to overcome the limitations of current treatment options of many diseases. However, delivery of these molecules still poses a great challenge to date. METHODS: In the present study, a multicompartmental...

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Detalles Bibliográficos
Autores principales:	Kriegel, Christina, Amiji, Mansoor M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365667/ https://www.ncbi.nlm.nih.gov/pubmed/23237848 http://dx.doi.org/10.1038/ctg.2011.1

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