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Transglutaminase-2 Interaction with Heparin: IDENTIFICATION OF A HEPARIN BINDING SITE THAT REGULATES CELL ADHESION TO FIBRONECTIN-TRANSGLUTAMINASE-2 MATRIX

Heparan sulfate proteoglycans are critical binding partners for extracellular tranglutaminase-2 (TG2), a multifunctional protein involved in tissue remodeling events related to organ fibrosis and cancer progression. We previously showed that TG2 has a strong affinity for heparan sulfate (HS)/heparin...

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Detalles Bibliográficos
Autores principales:	Lortat-Jacob, Hugues, Burhan, Izhar, Scarpellini, Alessandra, Thomas, Aline, Imberty, Anne, Vivès, Romain R., Johnson, Timothy, Gutierrez, Aldo, Verderio, Elisabetta A. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365763/ https://www.ncbi.nlm.nih.gov/pubmed/22442151 http://dx.doi.org/10.1074/jbc.M111.337089

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