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Novel Role of ADAMTS-5 Protein in Proteoglycan Turnover and Lipoprotein Retention in Atherosclerosis

Atherosclerosis is initiated by the retention of lipoproteins on proteoglycans in the arterial intima. However, the mechanisms leading to proteoglycan accumulation and lipoprotein retention are poorly understood. In this study, we set out to investigate the role of ADAMTS-5 (a disintegrin and metall...

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Detalles Bibliográficos
Autores principales:	Didangelos, Athanasios, Mayr, Ursula, Monaco, Claudia, Mayr, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365970/ https://www.ncbi.nlm.nih.gov/pubmed/22493487 http://dx.doi.org/10.1074/jbc.C112.350785

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