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p57(KIP2) control of actin cytoskeleton dynamics is responsible for its mitochondrial pro-apoptotic effect

p57 (Kip2, cyclin-dependent kinase inhibitor 1C), often found downregulated in cancer, is reported to hold tumor suppressor properties. Originally described as a cyclin-dependent kinase (cdk) inhibitor, p57(KIP2) has since been shown to influence other cellular processes, beyond cell cycle regulatio...

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Detalles Bibliográficos
Autores principales:	Kavanagh, E, Vlachos, P, Emourgeon, V, Rodhe, J, Joseph, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366085/ https://www.ncbi.nlm.nih.gov/pubmed/22592318 http://dx.doi.org/10.1038/cddis.2012.51

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