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Thermodynamic Control of Small RNA-Mediated Gene Silencing

Small interfering RNAs (siRNAs) and microRNAs (miRNAs) are key regulators of posttranscriptional gene silencing, which is referred to as RNA interference (RNAi) or RNA silencing. In RNAi, siRNA loaded onto the RNA-induced silencing complex (RISC) downreugulates target gene expression by cleaving mRN...

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Detalles Bibliográficos
Autores principales:	Ui-Tei, Kumiko, Nishi, Kenji, Takahashi, Tomoko, Nagasawa, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366367/ https://www.ncbi.nlm.nih.gov/pubmed/22675333 http://dx.doi.org/10.3389/fgene.2012.00101

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