Cargando…
Identification of cytosolic phosphodiesterases in the erythrocyte: A possible role for PDE5
BACKGROUND: Within erythrocytes (RBCs), cAMP levels are regulated by phosphodiesterases (PDEs). Increases in cAMP and ATP release associated with activation of β-adrenergic receptors (βARs) and prostacyclin receptors (IPRs) are regulated by PDEs 2, 4 and PDE 3, respectively. Here we establish the pr...
Autores principales: | Adderley, Shaquria P., Thuet, Kelly M., Sridharan, Meera, Bowles, Elizabeth A., Stephenson, Alan H., Ellsworth, Mary L., Sprague, Randy S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366467/ https://www.ncbi.nlm.nih.gov/pubmed/21525805 http://dx.doi.org/10.12659/MSM.881763 |
Ejemplares similares
-
Liposomal delivery of a phosphodiesterase 3 inhibitor rescues low oxygen-induced ATP release from erythrocytes of humans with type 2 diabetes
por: Dergunov, Sergey A., et al.
Publicado: (2015) -
Liposomal-delivery of phosphodiesterase 5 inhibitors augments UT-15C-stimulated ATP release from human erythrocytes()
por: Bowles, Elizabeth A., et al.
Publicado: (2017) -
Phosphodiesterases Regulate BAY 41-2272-Induced VASP Phosphorylation in Vascular Smooth Muscle Cells
por: Adderley, Shaquria P., et al.
Publicado: (2012) -
Toward a Multiscale Description of Microvascular Flow Regulation: O(2)-Dependent Release of ATP from Human Erythrocytes and the Distribution of ATP in Capillary Networks
por: Goldman, Daniel, et al.
Publicado: (2012) -
Phosphodiesterase (PDE)-4 Inhibitors and COPD Correlation with Cancer
por: Organtzis, John, et al.
Publicado: (2014)