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All in the Family: How the APPs Regulate Neurogenesis
Recent intriguing evidence suggests that metabolites of amyloid precursor protein (APP), mutated in familial forms of Alzheimer’s disease (AD), play critical roles in developmental and postnatal neurogenesis. Of note is soluble APPα (sAPPα) that regulates neural progenitor cell proliferation. The AP...
Autores principales: | Lazarov, Orly, Demars, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366480/ https://www.ncbi.nlm.nih.gov/pubmed/22675290 http://dx.doi.org/10.3389/fnins.2012.00081 |
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