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Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi

Little is known about the impact of indoor residual spraying (IRS) in areas with intense malaria transmission such as sub-Saharan Africa. In Malawi, IRS with lambda-cyhalothrin has been applied annually in an area of intense year-long transmission since 2007. We evaluated the impact of IRS on parasi...

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Autores principales: Skarbinski, Jacek, Mwandama, Dyson, Wolkon, Adam, Luka, Madalitso, Jafali, James, Smith, Alison, Mzilahowa, Themba, Gimnig, John, Campbell, Carl, Chiphwanya, John, Ali, Doreen, Mathanga, Don P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366547/
https://www.ncbi.nlm.nih.gov/pubmed/22665608
http://dx.doi.org/10.4269/ajtmh.2012.11-0621
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author Skarbinski, Jacek
Mwandama, Dyson
Wolkon, Adam
Luka, Madalitso
Jafali, James
Smith, Alison
Mzilahowa, Themba
Gimnig, John
Campbell, Carl
Chiphwanya, John
Ali, Doreen
Mathanga, Don P.
author_facet Skarbinski, Jacek
Mwandama, Dyson
Wolkon, Adam
Luka, Madalitso
Jafali, James
Smith, Alison
Mzilahowa, Themba
Gimnig, John
Campbell, Carl
Chiphwanya, John
Ali, Doreen
Mathanga, Don P.
author_sort Skarbinski, Jacek
collection PubMed
description Little is known about the impact of indoor residual spraying (IRS) in areas with intense malaria transmission such as sub-Saharan Africa. In Malawi, IRS with lambda-cyhalothrin has been applied annually in an area of intense year-long transmission since 2007. We evaluated the impact of IRS on parasitemia and anemia prevalence in children less than five years of age by using a cross-sectional household survey conducted in 2009, six months after the second IRS spray round. We measured malaria parasitemia and anemia (hemoglobin level < 11 g/dL) in 899 children less than five years of age and used binomial regression to assess the impact of IRS by comparing children living in a household sprayed with IRS (direct IRS) with those in a household not sprayed with IRS, but in an IRS area (indirect IRS) and those living in a household not sprayed with IRS and not in an IRS area (no IRS). In the IRS area, 77% of households reported receiving IRS. Adjusting for bed net use, house construction, and socioeconomic status, we found that receiving direct IRS and indirect IRS were significantly associated with a 33% (95% confidence interval [CI] = 1–54%) and 46% (95% CI = 20–64%) reduction in parasitemia and a 21% (95% CI = 4–34%) and 30% (95% CI = 12–45%) reduction in anemia prevalence, respectively.
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spelling pubmed-33665472012-07-12 Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi Skarbinski, Jacek Mwandama, Dyson Wolkon, Adam Luka, Madalitso Jafali, James Smith, Alison Mzilahowa, Themba Gimnig, John Campbell, Carl Chiphwanya, John Ali, Doreen Mathanga, Don P. Am J Trop Med Hyg Articles Little is known about the impact of indoor residual spraying (IRS) in areas with intense malaria transmission such as sub-Saharan Africa. In Malawi, IRS with lambda-cyhalothrin has been applied annually in an area of intense year-long transmission since 2007. We evaluated the impact of IRS on parasitemia and anemia prevalence in children less than five years of age by using a cross-sectional household survey conducted in 2009, six months after the second IRS spray round. We measured malaria parasitemia and anemia (hemoglobin level < 11 g/dL) in 899 children less than five years of age and used binomial regression to assess the impact of IRS by comparing children living in a household sprayed with IRS (direct IRS) with those in a household not sprayed with IRS, but in an IRS area (indirect IRS) and those living in a household not sprayed with IRS and not in an IRS area (no IRS). In the IRS area, 77% of households reported receiving IRS. Adjusting for bed net use, house construction, and socioeconomic status, we found that receiving direct IRS and indirect IRS were significantly associated with a 33% (95% confidence interval [CI] = 1–54%) and 46% (95% CI = 20–64%) reduction in parasitemia and a 21% (95% CI = 4–34%) and 30% (95% CI = 12–45%) reduction in anemia prevalence, respectively. The American Society of Tropical Medicine and Hygiene 2012-06-01 /pmc/articles/PMC3366547/ /pubmed/22665608 http://dx.doi.org/10.4269/ajtmh.2012.11-0621 Text en ©The American Society of Tropical Medicine and Hygiene This is an Open Access article distributed under the terms of the American Society of Tropical Medicine and Hygiene's Re-use License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Skarbinski, Jacek
Mwandama, Dyson
Wolkon, Adam
Luka, Madalitso
Jafali, James
Smith, Alison
Mzilahowa, Themba
Gimnig, John
Campbell, Carl
Chiphwanya, John
Ali, Doreen
Mathanga, Don P.
Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi
title Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi
title_full Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi
title_fullStr Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi
title_full_unstemmed Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi
title_short Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi
title_sort impact of indoor residual spraying with lambda-cyhalothrin on malaria parasitemia and anemia prevalence among children less than five years of age in an area of intense, year-round transmission in malawi
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366547/
https://www.ncbi.nlm.nih.gov/pubmed/22665608
http://dx.doi.org/10.4269/ajtmh.2012.11-0621
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