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Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems
Marine systems are very diverse and recognized as being sources of a wide range of biomolecules. This review provides an overview of metabolite profiling based on mass spectrometry (MS) approaches in marine organisms and their environments, focusing on recent advances in the field. We also point out...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366679/ https://www.ncbi.nlm.nih.gov/pubmed/22690147 http://dx.doi.org/10.3390/md10040849 |
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author | Goulitquer, Sophie Potin, Philippe Tonon, Thierry |
author_facet | Goulitquer, Sophie Potin, Philippe Tonon, Thierry |
author_sort | Goulitquer, Sophie |
collection | PubMed |
description | Marine systems are very diverse and recognized as being sources of a wide range of biomolecules. This review provides an overview of metabolite profiling based on mass spectrometry (MS) approaches in marine organisms and their environments, focusing on recent advances in the field. We also point out some of the technical challenges that need to be overcome in order to increase applications of metabolomics in marine systems, including extraction of chemical compounds from different matrices and data management. Metabolites being important links between genotype and phenotype, we describe added value provided by integration of data from metabolite profiling with other layers of omics, as well as their importance for the development of systems biology approaches in marine systems to study several biological processes, and to analyze interactions between organisms within communities. The growing importance of MS-based metabolomics in chemical ecology studies in marine ecosystems is also illustrated. |
format | Online Article Text |
id | pubmed-3366679 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-33666792012-06-11 Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems Goulitquer, Sophie Potin, Philippe Tonon, Thierry Mar Drugs Review Marine systems are very diverse and recognized as being sources of a wide range of biomolecules. This review provides an overview of metabolite profiling based on mass spectrometry (MS) approaches in marine organisms and their environments, focusing on recent advances in the field. We also point out some of the technical challenges that need to be overcome in order to increase applications of metabolomics in marine systems, including extraction of chemical compounds from different matrices and data management. Metabolites being important links between genotype and phenotype, we describe added value provided by integration of data from metabolite profiling with other layers of omics, as well as their importance for the development of systems biology approaches in marine systems to study several biological processes, and to analyze interactions between organisms within communities. The growing importance of MS-based metabolomics in chemical ecology studies in marine ecosystems is also illustrated. MDPI 2012-04-05 /pmc/articles/PMC3366679/ /pubmed/22690147 http://dx.doi.org/10.3390/md10040849 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Goulitquer, Sophie Potin, Philippe Tonon, Thierry Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems |
title | Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems |
title_full | Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems |
title_fullStr | Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems |
title_full_unstemmed | Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems |
title_short | Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems |
title_sort | mass spectrometry-based metabolomics to elucidate functions in marine organisms and ecosystems |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366679/ https://www.ncbi.nlm.nih.gov/pubmed/22690147 http://dx.doi.org/10.3390/md10040849 |
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