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Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase

RING E3 ligases are proteins that must selectively recruit an E2-conjugating enzyme and facilitate ubiquitin transfer to a substrate. It is not clear how a RING E3 ligase differentiates a naked E2 enzyme from the E2∼ubiquitin-conjugated form or how this is altered upon ubiquitin transfer. RING-box p...

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Detalles Bibliográficos
Autores principales:	Spratt, Donald E., Wu, Kenneth, Kovacev, Jordan, Pan, Zhen-Qiang, Shaw, Gary S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366790/ https://www.ncbi.nlm.nih.gov/pubmed/22433864 http://dx.doi.org/10.1074/jbc.M112.353748

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