Cargando…
3′-Phosphoadenosine 5′-Phosphosulfate (PAPS) Synthases, Naturally Fragile Enzymes Specifically Stabilized by Nucleotide Binding
Activated sulfate in the form of 3′-phosphoadenosine 5′-phosphosulfate (PAPS) is needed for all sulfation reactions in eukaryotes with implications for the build-up of extracellular matrices, retroviral infection, protein modification, and steroid metabolism. In metazoans, PAPS is produced by bifunc...
Autores principales: | van den Boom, Johannes, Heider, Dominik, Martin, Stephen R., Pastore, Annalisa, Mueller, Jonathan W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366831/ https://www.ncbi.nlm.nih.gov/pubmed/22451673 http://dx.doi.org/10.1074/jbc.M111.325498 |
Ejemplares similares
-
Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1
por: Mueller, Jonathan W., et al.
Publicado: (2018) -
Analysis of the Human 3’-Phosphoadenosine 5’-Phosphosulfate Synthase Genes
por: Campbell, W.G., et al.
Publicado: (2002) -
Nucleotide Binding by Lhs1p Is Essential for Its Nucleotide Exchange Activity and for Function in Vivo
por: de Keyzer, Jeanine, et al.
Publicado: (2009) -
Bacterial Over-Expression and Purification of the 3′phosphoadenosine 5′phosphosulfate (PAPS) Reductase Domain of Human FAD Synthase: Functional Characterization and Homology Modeling
por: Miccolis, Angelica, et al.
Publicado: (2012) -
3′-Phosphoadenosine
5′-Phosphosulfate
Allosterically Regulates Sulfotransferase Turnover
por: Wang, Ting, et al.
Publicado: (2014)