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The role of Na(+)/H(+ )exchanger in Ca(2+ )overload and ischemic myocardial damage in hearts from type 2 diabetic db/db mice

BACKGROUND: A higher increase in intracellular Na(+ )via Na(+)/H(+ )exchanger (NHE) during ischemia has been reported in type 2 diabetic mouse hearts. We investigated the role of NHE in inducing changes in cytoplasmic Ca(2+ )concentration ([Ca(2+)](i)) and alterations in ventricular function during...

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Detalles Bibliográficos
Autores principales:	Anzawa, Ryuko, Seki, Shingo, Nagoshi, Tomohisa, Taniguchi, Ikuo, Feuvray, Danielle, Yoshimura, Michihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366908/ https://www.ncbi.nlm.nih.gov/pubmed/22490613 http://dx.doi.org/10.1186/1475-2840-11-33

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