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Elimination of Specific miRNAs by Naked 14-nt sgRNAs

tRNase Z(L)-utilizing efficacious gene silencing (TRUE gene silencing) is a newly developed technology to suppress mammalian gene expression. TRUE gene silencing works on the basis of a unique enzymatic property of mammalian tRNase Z(L), which is that it can recognize a pre-tRNA-like or micro-pre-tR...

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Detalles Bibliográficos
Autores principales:	Takahashi, Masayuki, Elbarbary, Reyad A., Abe, Mayumi, Sato, Mari, Yoshida, Tetsuo, Yamada, Yoji, Tamura, Masato, Nashimoto, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366928/ https://www.ncbi.nlm.nih.gov/pubmed/22675569 http://dx.doi.org/10.1371/journal.pone.0038496

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