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Hepatocyte Growth Factor Increases Osteopontin Expression in Human Osteoblasts through PI3K, Akt, c-Src, and AP-1 Signaling Pathway

BACKGROUND: Hepatocyte growth factor (HGF) has been demonstrated to stimulate osteoblast proliferation and participated bone remodeling. Osteopontin (OPN) is a secreted phosphoglycoprotein that belongs to the SIBLING family and is present during bone mineralization. However, the effects of HGF on OP...

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Detalles Bibliográficos
Autores principales:	Chen, Hsien-Te, Tsou, Hsi-Kai, Chang, Chia-Hao, Tang, Chih-Hsin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366938/ https://www.ncbi.nlm.nih.gov/pubmed/22675553 http://dx.doi.org/10.1371/journal.pone.0038378

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