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Disease-Related Cardiac Troponins Alter Thin Filament Ca(2+) Association and Dissociation Rates

The contractile response of the heart can be altered by disease-related protein modifications to numerous contractile proteins. By utilizing an IAANS labeled fluorescent troponin C, [Image: see text], we examined the effects of ten disease-related troponin modifications on the Ca(2+) binding propert...

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Detalles Bibliográficos
Autores principales:	Liu, Bin, Tikunova, Svetlana B., Kline, Kristopher P., Siddiqui, Jalal K., Davis, Jonathan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366952/ https://www.ncbi.nlm.nih.gov/pubmed/22675533 http://dx.doi.org/10.1371/journal.pone.0038259

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