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Immunogenicity of Self-Associated Aggregates and Chemically Cross-Linked Conjugates of the 42 kDa Plasmodium falciparum Merozoite Surface Protein-1

Self-associated protein aggregates or cross-linked protein conjugates are, in general, more immunogenic than oligomeric or monomeric forms. In particular, the immunogenicity in mice of a recombinant malaria transmission blocking vaccine candidate, the ookinete specific Plasmodium falciparum 25 kDa p...

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Detalles Bibliográficos
Autores principales: Qian, Feng, Reiter, Karine, Zhang, Yanling, Shimp, Richard L., Nguyen, Vu, Aebig, Joan A., Rausch, Kelly M., Zhu, Daming, Lambert, Lynn, Mullen, Gregory E. D., Martin, Laura B., Long, Carole A., Miller, Louis H., Narum, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366955/
https://www.ncbi.nlm.nih.gov/pubmed/22675476
http://dx.doi.org/10.1371/journal.pone.0036996