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Nucleolin Inhibits G4 Oligonucleotide Unwinding by Werner Helicase

BACKGROUND: The Werner protein (WRNp), a member of the RecQ helicase family, is strongly associated with the nucleolus, as is nucleolin (NCL), an important nucleolar constituent protein. Both WRNp and NCL respond to the effects of DNA damaging agents. Therefore, we have investigated if these nuclear...

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Detalles Bibliográficos
Autores principales: Indig, Fred E., Rybanska, Ivana, Karmakar, Parimal, Devulapalli, Chakravarty, Fu, Haiqing, Carrier, France, Bohr, Vilhelm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366963/
https://www.ncbi.nlm.nih.gov/pubmed/22675465
http://dx.doi.org/10.1371/journal.pone.0035229