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CXCR3 Antagonism of SDF-1(5-67) Restores Trabecular Function and Prevents Retinal Neurodegeneration in a Rat Model of Ocular Hypertension
Glaucoma, the most common cause of irreversible blindness, is a neuropathy commonly initiated by pathological ocular hypertension due to unknown mechanisms of trabecular meshwork degeneration. Current antiglaucoma therapy does not target the causal trabecular pathology, which may explain why treatme...
Autores principales: | Denoyer, Alexandre, Godefroy, David, Célérier, Isabelle, Frugier, Julie, Degardin, Julie, Harrison, Jeffrey K., Brignole-Baudouin, Francoise, Picaud, Serge, Baleux, Francoise, Sahel, José A., Rostène, William, Baudouin, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366966/ https://www.ncbi.nlm.nih.gov/pubmed/22675496 http://dx.doi.org/10.1371/journal.pone.0037873 |
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