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Functional Characterization of a First Avian Cytochrome P450 of the CYP2D Subfamily (CYP2D49)
The CYP2D family members are instrumental in the metabolism of 20–25% of commonly prescribed drugs. Although many CYP2D isoforms have been well characterized in other animal models, research concerning the chicken CYP2Ds is limited. In this study, a cDNA encoding a novel CYP2D enzyme (CYP2D49) was c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366968/ https://www.ncbi.nlm.nih.gov/pubmed/22675558 http://dx.doi.org/10.1371/journal.pone.0038395 |