Cargando…

Novel RNA base pair with higher specificity using single selenium atom

Specificity of nucleobase pairing provides essential foundation for genetic information storage, replication, transcription and translation in all living organisms. However, the wobble base pairs, where U in RNA (or T in DNA) pairs with G instead of A, might compromise the high specificity of the ba...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Huiyan, Sheng, Jia, Hassan, Abdalla E. A., Jiang, Sibo, Gan, Jianhua, Huang, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Synthetic Biology and Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367167/ https://www.ncbi.nlm.nih.gov/pubmed/22323523 http://dx.doi.org/10.1093/nar/gks010

Ejemplares similares

Derivatization of DNAs with selenium at 6-position of guanine for function and crystal structure studies
por: Salon, Jozef, et al.
Publicado: (2008)

Highly specific unnatural base pair systems as a third base pair for PCR amplification
por: Yamashige, Rie, et al.
Publicado: (2012)

Synthesis, structure and imaging of oligodeoxyribonucleotides with tellurium-nucleobase derivatization
por: Sheng, Jia, et al.
Publicado: (2011)

Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs
por: Ashworth, Justin, et al.
Publicado: (2010)

Pairing of single mutations yields obligate Cre-type site-specific recombinases
por: Hoersten, Jenna, et al.
Publicado: (2021)

Base pair opening kinetics study of the aegPNA:DNA hydrid duplex containing a site-specific GNA-like chiral PNA monomer
por: Seo, Yeo-Jin, et al.
Publicado: (2011)

The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation
por: Hwang, Gil Tae, et al.
Publicado: (2009)

Properties of pseudo-complementary DNA substituted with weakly pairing analogs of guanine or cytosine
por: Lahoud, Georges, et al.
Publicado: (2008)

Aromatic N versus aromatic F: bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs
por: Koller, Alrun N., et al.
Publicado: (2010)

Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine(†)
por: Bhamra, Inder, et al.
Publicado: (2012)

Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo(−) ) DNA polymerase
por: Ogata, Shintaro, et al.
Publicado: (2009)

Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling
por: Motorin, Yuri, et al.
Publicado: (2011)

Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet
por: Dhami, Kirandeep, et al.
Publicado: (2014)

Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA
por: Guza, Rebecca, et al.
Publicado: (2011)

A new usage of functionalized oligodeoxynucleotide probe for site-specific modification of a guanine base within RNA
por: Onizuka, Kazumitsu, et al.
Publicado: (2010)

Cell-free co-production of an orthogonal transfer RNA activates efficient site-specific non-natural amino acid incorporation
por: Albayrak, Cem, et al.
Publicado: (2013)

Logic integration of mRNA signals by an RNAi-based molecular computer
por: Xie, Zhen, et al.
Publicado: (2010)

Directed evolution of recombinase specificity by split gene reassembly
por: Gersbach, Charles A., et al.
Publicado: (2010)

Chimeric TALE recombinases with programmable DNA sequence specificity
por: Mercer, Andrew C., et al.
Publicado: (2012)

Comprehensive analysis of the specificity of transcription activator-like effector nucleases
por: Juillerat, Alexandre, et al.
Publicado: (2014)

A directed evolution design of a GCG-specific DNA hemimethylase
por: Gerasimaitė, Rūta, et al.
Publicado: (2009)

MegaTevs: single-chain dual nucleases for efficient gene disruption
por: Wolfs, Jason M., et al.
Publicado: (2014)

A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia
por: Mallikaratchy, Prabodhika R., et al.
Publicado: (2011)

Density-dependent cooperative non-specific binding in solid-phase SELEX affinity selection
por: Ozer, Abdullah, et al.
Publicado: (2013)

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer
por: Pasternak, Anna, et al.
Publicado: (2011)

DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells
por: Attaluri, Sivaprasad, et al.
Publicado: (2010)

Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants
por: Sirk, Shannon J., et al.
Publicado: (2014)

Stabilization of unstable CGC(+) triplex DNA by single-walled carbon nanotubes under physiological conditions
por: Song, Yujun, et al.
Publicado: (2011)

A single-input binary counting module based on serine integrase site-specific recombination
por: Zhao, Jia, et al.
Publicado: (2019)

Specific recognition and stabilization of monomeric and multimeric G-quadruplexes by cationic porphyrin TMPipEOPP under molecular crowding conditions
por: Zhu, Li-Na, et al.
Publicado: (2013)

Quantitative design and experimental validation for a single-molecule DNA nanodevice transformable among three structural states
por: Komiya, Ken, et al.
Publicado: (2010)

Synthesis and characterization of oligodeoxyribonucleotides containing a site-specifically incorporated N(6)-carboxymethyl-2′-deoxyadenosine or N(4)-carboxymethyl-2′-deoxycytidine
por: Wang, Jianshuang, et al.
Publicado: (2010)

Triplex inducer-directed self-assembly of single-walled carbon nanotubes: a triplex DNA-based approach for controlled manipulation of nanostructures
por: Zhao, Chao, et al.
Publicado: (2011)

A single-label phenylpyrrolocytidine provides a molecular beacon-like response reporting HIV-1 RT RNase H activity
por: Wahba, Alexander S., et al.
Publicado: (2010)

Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing
por: Deleavey, Glen F., et al.
Publicado: (2010)

Identification of antisense RNA stem–loops that inhibit RNA–protein interactions using a bacterial reporter system
por: Yano, Akiko, et al.
Publicado: (2010)

Kinetics and thermodynamics of DNA hybridization on gold nanoparticles
por: Chen, Chunlai, et al.
Publicado: (2009)

Stimuli-responsive controlled-release system using quadruplex DNA-capped silica nanocontainers
por: Chen, Cuie, et al.
Publicado: (2011)

Reliable semi-synthesis of hydrolysis-resistant 3′-peptidyl-tRNA conjugates containing genuine tRNA modifications
por: Graber, Dagmar, et al.
Publicado: (2010)

A ribozyme that triphosphorylates RNA 5′-hydroxyl groups
por: Moretti, Janina E., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_pv8bsi85lq698tc82jvt95r67h