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A tunable zinc finger-based framework for Boolean logic computation in mammalian cells
The ability to perform molecular-level computation in mammalian cells has the potential to enable a new wave of sophisticated cell-based therapies and diagnostics. To this end, we developed a Boolean logic framework utilizing artificial Cys(2)–His(2) zinc finger transcription factors (ZF-TFs) as com...
Autores principales: | Lohmueller, Jason J., Armel, Thomas Z., Silver, Pamela A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367183/ https://www.ncbi.nlm.nih.gov/pubmed/22323524 http://dx.doi.org/10.1093/nar/gks142 |
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